The San Francisco Giants wrap up what figures to be a meaningful late-September home date on Tuesday, September 22, when they host the Minnesota Twins at Oracle Park with first pitch scheduled for 9:45 PM ET. Anthony Molina takes the ball for San Francisco against Minnesota's Taj Bradley in a matchup that gives the Giants a chance to make a statement on their home turf with the regular season winding toward its final days. Catch the action on NBC Sports Bay Area or tune in on KNBR 680.

Pitching Matchup: Anthony Molina vs. Taj Bradley

Molina gets the nod for the Giants in what is a significant opportunity for the young right-hander. Stats on his 2026 season are not yet confirmed ahead of first pitch, but his presence in the rotation this late in September suggests the organization trusts him to compete in a meaningful spot. The Giants will need length from him — a short outing puts pressure on a bullpen that has been asked to carry a heavy workload throughout the season.

Bradley takes the mound for Minnesota. The former Tampa Bay pitching prospect has shown stretches of genuine upside in his career, with a fastball-slider combination that can give right-handed hitters fits. Whether he carries that form into Oracle Park remains to be seen, but the Giants' lineup will need to be patient and work counts early.

Giants Starting Lineup

• 1. Drew Gilbert, CF
• 2. Jonah Cox, 2B
• 3. Victor Bericoto, 1B
• 4. Turner Hill, LF
• 5. Bo Davidson, DH
• 6. Shay Whitcomb, 3B
• 7. Scott Bandura, RF
• 8. Drew Cavanaugh, C
• 9. Christian Koss, SS

Keys to Watch for San Francisco

Bericoto and Hill Need to Carry the Middle of the Order

With Victor Bericoto slotted third and Turner Hill batting cleanup, the Giants are leaning on that pairing to drive the offense. Both players need to be productive against Bradley, particularly in situations where runners are on base. If those two can put together quality at-bats early, it sets up the rest of the lineup to contribute.

Drew Gilbert Sets the Tone at the Top

Gilbert leading off in center field is a key piece of this lineup's construction. His ability to get on base and create early pressure on Bradley will dictate how the first few innings unfold. A Giants offense that manufactures runs with speed and contact rather than waiting on the long ball tends to perform better at Oracle Park, where the dimensions make pure power a harder sell.

Molina Must Limit Traffic

The Giants win when their starter works deep into games and keeps the lineup manageable. Molina's command and ability to work ahead in counts will be the central storyline on the pitching side. Walks early against a Twins lineup that can string together hits become a real problem in a hurry.

Prediction

This is a winnable game for San Francisco. The home crowd at Oracle Park gives the Giants a genuine edge, and with the lineup constructed the way it is — Gilbert at the top, legitimate run-producers in the three and four holes — there is enough offense to support Molina if he does his job. The Giants take this one, 4-2.